Growth Factor Analog Peptide

IGF-1 LR3

Size: 1MG

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IGF-1 LR3 GREYLINE research vial
$139.982 vials · $69.99 per vial
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2
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For research use only. Not for human or veterinary use.

Product Description

IGF-1 LR3 Long R3 IGF-I is an engineered IGF-I analog containing an N-terminal extension and an arginine substitution at position 3. Primary animal, cell-culture, and analytical studies distinguish it from native IGF-I and examine its altered interaction with IGF-binding proteins. No authoritative public chemical record was found that fixes a single salt form, formula, or molecular mass for this catalog material.

Certificate of Analysis

Lot-specific analytical results and downloadable documentation

Compound Information

Technical specifications

Molecular Profile

What is IGF-1 LR3?

Type
Recombinant 83-residue IGF-I analog
CAS number
Molecular weight
Amino acids
83
Molecular formula
NCBI PubMed: Long R3 IGF-I
Storage Requirements

Stability Information

Formulation-specific stability unknownProtect from lightKeep sealed and dry
Lyophilized / unopenedNo product-specific shelf life supplied; follow a qualified laboratory SOP.
Reconstituted / in solutionNo authoritative hold time supplied; use a validated laboratory protocol.

Recombinant-protein handling is highly formulation-dependent.

Sources & References

Peer-reviewed and authoritative records

Journal of Endocrinology

Primary research

Superior potency of infused IGF-I analogues which bind poorly to IGF-binding proteins is maintained when administered by injection

Tomas FM, Lemmey AB, Read LC, Ballard FJ

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Molecular Biotechnology

Primary research

LONG R3IGF-I as a more potent alternative to insulin in serum-free culture of HEK293 cells

Voorhamme D, Yandell CA

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Journal of Endocrinology

Primary research

IGF-I variants which bind poorly to IGF-binding proteins show more potent and prolonged hypoglycaemic action than native IGF-I in pigs and marmoset monkeys

Tomas FM, Walton PE, Dunshea FR, Ballard FJ

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Drug Testing and Analysis

Primary analytical research

Detection of LongR3-IGF-I, Des(1-3)-IGF-I, and R3-IGF-I using immunopurification and high resolution mass spectrometry for antidoping purposes

Mongongu C, et al.

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American Journal of Physiology-Endocrinology and Metabolism

Primary research

IGF-1 LR3 does not promote growth in late-gestation growth-restricted fetal sheep

White A, et al.

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Important Research Notice

Not for human consumption. This product is sold exclusively for laboratory, analytical, and educational research purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

Research information presented on this page is provided for educational reference and should not be interpreted as medical advice or as a product claim.

By purchasing this product, the customer confirms that it will be handled and used only by qualified individuals in accordance with all applicable laws and laboratory procedures.

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